Biotech ETFs
The funds
Expense ratio = the yearly fee, as a share of your money in the fund. Top 10 = share of the fund in its 10 largest holdings.
| Fund | Issuer | Expense ratio | Holdings | Top 10 | As of |
|---|---|---|---|---|---|
State Street SPDR S&P Biotech ETFXBI |
State Street | — | Holdings not yet filed with the SEC | ||
iShares Biotechnology ETFIBB |
iShares | — | Holdings not yet filed with the SEC | ||
ARK Genomic Revolution ETFARKG |
ARK | — | Holdings not yet filed with the SEC | ||
VanEck Biotech ETFBBH |
VanEck | — | Holdings not yet filed with the SEC | ||
ALPS Medical Breakthroughs ETFSBIO |
ALPS | — | Holdings not yet filed with the SEC | ||
How this works & disclosures
The fund list is picked by Coteau from US-listed ETFs registered with the SEC; leveraged and inverse funds are left out, and being on the list isn’t a view on the fund. Holdings are from each fund’s latest public Form N-PORT on SEC EDGAR (as-of dates in the table) and change over time; funds launched in the last few months may not have filed one yet.
Overlap by weight adds up, for every holding both funds own, the smaller of its two weights. Sub-themes are assigned by Coteau from each company’s main line of business; anything not assigned is in Other, and bars leave out cash. Expense ratios come from each fund’s prospectus (Form 485BPOS) fee table on SEC EDGAR; a dash means it wasn’t machine-readable there.
Data from SEC Form N-PORT, the holdings report funds file with the SEC each quarter; the SEC makes it public about 60 days after the quarter ends. Holdings change; this may be out of date. Coteau describes what funds hold and how they have done; it does not manage money or give advice. Not investment advice. Full disclosures
Data from SEC filings. Holdings change; this may be out of date. Not investment advice. Disclosures
Independent research · Not investment advice · Important disclosures · Contact desk@coteau.app
Coteau Systematic Strategies publishes stock research and model portfolios. Results are hypothetical unless marked Live. Data: Yahoo Finance (15-min delayed), SEC EDGAR and the House Clerk.
Beta 0.9 · Oct 21, 2026