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RYTM

RYTM

Rhythm Pharmaceuticals, Inc.
$88.23
+2.39% 2026-10-19
Healthcare
-33%-20%-8%+5%+17%Oct 2025Apr 2026Oct 2026
RYTMSPY
1W
-1.8%
1M
-9.7%
3M
-15.7%
6M
+0.6%
YTD
-17.6%
1Y
-20.0%

Grades vs sector

Momentum
no data
–

Percentile within its GICS sector across the S&P 1500.
Growth
no data
–

Percentile within its GICS sector across the S&P 1500.
Value
no data
–

Percentile within its GICS sector across the S&P 1500.
Profitability
no data
–

Percentile within its GICS sector across the S&P 1500.
Revisions
no data
–

30-day change in analysts' current-year EPS estimate; graded across covered stocks.

Our models

Not held by any of our 3 live models right now.

Momentum Top 15
not ranked (outside this model's universe or screens)
Quality Growth
not ranked (outside this model's universe or screens)
Momentum Blend
not in the current book

Key stats

Market cap$6.1B
P/E (trailing)–
P/E (forward)-140.3
52-week range74.50 – 122.20
Revenue growth (YoY, latest qtr)+46.9%
Dividend yield0.00%
Analyst consensusStrong Buy (18)
Mean price target$143.94 (+63%)

Valuation & fundamentals

Bottom line
No cash-flow valuation
Model read-out from the numbers below, not advice. Score +1 (DCF counts double).
•Piotroski F-score5/9
▲Altman Z11.8 (safe)
▲Analyst target+63% (18 analysts)

Discounted cash flow

Trailing free cash flow is negative or missing, so a cash-flow DCF isn't meaningful by default. You can enter your own assumptions below.
Reverse DCFfor context, not a signal
Trailing free cash flow is zero or negative, so there's no growth rate to solve for. The price is betting on a turnaround to positive cash flow.
Edit assumptions · recalculates instantly
Your value per share–

Free cash flow = operating cash flow − capital spending, trailing 12 months (TTM to 2026-06-30). Growth default: average of 3-year revenue CAGR and latest revenue growth, capped at 30%. Years 6–10 fade linearly to terminal growth. Discount rate = 4.25% risk-free assumption + beta 2.01 × 5% equity premium, kept within 7–13%. Bear: lower growth, +1 pt discount, 2% terminal. Bull: higher growth, −1 pt, 3%.

Multiples vs sector

Forward EPS $-0.63 vs trailing $-3.12. Forward P/E uses analysts' next-12-month estimate.

Quality & financial health

Gross margin
89.0%
Operating margin
-83.6%
FCF margin
-44.3%
Net margin
-85.6%
Return on equity
-199.4%
Return on invested capital
–
Net debt / EBITDA
–
Current ratio
3.5×
Interest cover
-10.9×
Cash conversion (OCF/NI)
–
Piotroski F-score 5/9 · last two fiscal years
✗ Positive net income✗ Positive operating cash flow✓ Return on assets improved✓ Cash flow above net income✓ Long-term debt / assets fell✓ Current ratio improved✗ No share dilution✗ Gross margin improved✓ Asset turnover improved

Altman Z-score 11.8 (safe zone; above 3.0 = safe, below 1.8 = distress). Not meaningful for banks and insurers.

Analysts

Mean target
$144
+63%
Analysts
18
Strong Buy
Range
$120–$206
low – high
● price · ◆ mean target

Annual history

FYRevenueNet incomeFree cash flow
2025$189.8M$-196.5M$-116.6M
2024$130.1M$-260.6M$-113.9M
2023$77.4M$-184.7M$-136.2M
2022$23.6M$-181.1M$-173.7M
2021$3.2M$-69.6M$-146.4M
2020$0$-134.0M$-122.2M

From the company's 10-K filings via SEC XBRL. 3-year revenue CAGR +100.2%.

Earnings

Next report: 2026-11-03 · before open · EPS est -0.74
24-1125-0225-0525-0825-1126-0226-0526-08-0.870.00
EstimateActual (beat)Actual (miss)
ReportEPS estActualSurprise
2026-08-04-0.83-0.73+12.3%
2026-05-05-0.86-0.83+3.6%
2026-02-26-0.78-0.73+6.4%
2025-11-04-0.73-0.82-11.7%
2025-08-05-0.67-0.75-12.1%
2025-05-07-0.68-0.81-19.4%
2025-02-26-0.73-0.72+1.4%
2024-11-05-0.87-0.73+16.0%

Quarterly revenue

QuarterRevenueYoY
2026-06-30$71.3M+46.9%
2026-03-31$60.1M–
2025-12-31$57.3M–
2025-09-30$51.3M–
2025-06-30$48.5M–

Analyst actions

William Blair
2026-10-16 · init
→ Outperform
JP Morgan
2026-10-15 · main
Overweight → Overweight
PT $145
HC Wainwright & Co.
2026-10-12 · main
Buy → Buy
PT $130
RBC Capital
2026-10-08 · main
Outperform → Outperform
PT $159
Deutsche Bank
2026-08-28 · init
→ Hold
PT $120
JP Morgan
2026-08-07 · main
Overweight → Overweight
PT $146

Insider trades

Meeker David P
Director, President and CEO · 2026-09-14
SELL
$655.1K
Meeker David P
Director, President and CEO · 2026-09-14
SELL
$3.1M
Meeker David P
Director, President and CEO · 2026-09-14
SELL
$899.6K
Meeker David P
Director, President and CEO · 2026-09-14
SELL
$190.0K
Meeker David P
Director, President and CEO · 2026-09-14
SELL
$241.9K
Smith Hunter C
Chief Financial Officer · 2026-08-31
SELL
$2.4M
Smith Hunter C
Chief Financial Officer · 2026-08-31
SELL
$1.2M
Smith Hunter C
Chief Financial Officer · 2026-08-31
SELL
$3.0M
Shulman Joseph
Chief Technical Officer · 2026-08-13
SELL
$608.2K
Garfield Alastair
Chief Scientific Officer · 2026-08-13
SELL
$233.0K
Garfield Alastair
Chief Scientific Officer · 2026-08-13
SELL
$182.2K
Garfield Alastair
Chief Scientific Officer · 2026-08-13
SELL
$402.2K

News

Rhythm Pharmaceuticals Launches Hypothalamic Obesity Treatment in Japan
MT Newswires · Oct 14
Rhythm Pharmaceuticals Announces Commercial Launch of IMCIVREE® (setmelanotide) in Japan for Patients with Acquired Hypothalamic Obesity
GlobeNewswire · Oct 13
Rhythm Pharmaceuticals (RYTM) Upgraded to Buy: Here's What You Should Know
Zacks · Oct 13
How Investors May Respond To Rhythm Pharmaceuticals (RYTM) Progress In Prader-Willi And Genetically Defined Obesity Therapies
Simply Wall St. · Oct 12
Prader-Willi Syndrome Market to Expand by 2036 as New Therapeutic Opportunities Address Unmet Clinical Needs | DelveInsight
PR Newswire · Oct 12
Rhythm's Imcivree Launch in Hypothalamic Obesity Encouraging, RBC Says
MT Newswires · Oct 08
RBC Lifts Price Target on Rhythm Pharmaceuticals to $159 From $155, Keeps Outperform, Speculative Risk
MT Newswires · Oct 08
Rhythm Pharmaceuticals Gains Health Canada Approval for Imcivree
MT Newswires · Sep 22

Stats refreshed 2026-10-19 19:02:36 ET from Yahoo Finance (yfinance). "–" means the data isn't available. Refresh now

coteau
Coteau Systematic StrategiesSystematic equity research and model portfolios.
Coteau Systematic Strategies publishes research, model portfolios and tools. It does not manage money or offer investment advice. Model results are hypothetical. Data: Yahoo Finance (delayed), SEC EDGAR.