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PRAX

PRAX

Praxis Precision Medicines, Inc.
$256.47
-3.03% Oct 21 close
Healthcare Compare
-6%+25%+57%+89%+121%Oct 2025Oct 2026Apr 2026
PRAXSPY
1W
+7.3%
1M
-14.2%
3M
-17.8%
6M
-24.0%
YTD
-13.0%
1Y
+35.0%

Live chart

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What they do

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance in the United States. The company's platforms include Cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies.

Healthcare · Biotechnology

For information only · Important disclosures

Grades vs sector

No sector grades for PRAX yet. Grades rank S&P 1500 stocks within their sector and refresh after each daily data run, so a stock outside that index or newly covered has none.

Our models

Held by 1 of 5 live models: New Highs Growth.

New Highs Growth
4.0% of the book
Held
Quality Growth
Outside this model's universe or screens
Momentum Top 15
Outside this model's universe or screens
Momentum Blend
Not in the current book
Coteau Long Book
Not in the current book
Why it's in the New Highs Growth

Qualified on Biotech, -25% from 52-week high, biotech, price-only entry, 12-1 momentum +569%.

What would knock it out: Drops out if it falls outside the top 25 at the next rebalance (Oct 30). In the latest preview (2026-10-20) it is outside the top 25.

News

More news
No recent headlines.

Key stats

Market value$7.3B
P/E (next 12 months, estimated)-27.5
52-week range$154.45 – $392.70
Dividend yieldNo dividend
Analyst consensusStrong Buy (21)
Average analyst price target$650.00 (+153%)
Valuation and fundamentals

Valuation & fundamentals

Bottom line
No cash-flow valuation
Model read-out from the numbers below, not advice. Score +0 (DCF counts double).
▼Piotroski F-score3/9
▲Altman Z87.7 (safe)
▲Analyst target+153% (21 analysts)

Discounted cash flow

Trailing free cash flow is negative or missing, so a cash-flow DCF isn't meaningful by default. You can enter your own assumptions below.
Reverse DCFfor context, not a signal
Trailing free cash flow is zero or negative, so there's no growth rate to solve for. The price is betting on a turnaround to positive cash flow.
Edit assumptions · recalculates instantly
Your value per share–

Free cash flow = operating cash flow − capital spending, trailing 12 months (FY to 2025-12-31). Growth default: average of 3-year revenue CAGR and latest revenue growth, capped at 30%. Years 6–10 fade linearly to terminal growth. Discount rate = 4.25% risk-free assumption + beta 2.81 × 5% equity premium, kept within 7–13%. Bear: lower growth, +1 pt discount, 2% terminal. Bull: higher growth, −1 pt, 3%.

Multiples vs sector

Forward EPS $-9.50 vs trailing $-12.95. Forward P/E uses analysts' next-12-month estimate.

Quality & financial health

Gross margin
–
Operating margin
–
FCF margin
–
Net margin
–
Return on equity
-25.3%
Return on invested capital
-51.3%
Net debt / EBITDA
–
Current ratio
15.7×
Interest cover
–
Cash conversion (OCF/NI)
–
Piotroski F-score 3/9 · last two fiscal years
✗ Positive net income✗ Positive operating cash flow✓ Return on assets improved✓ Cash flow above net income✓ Long-term debt / assets fell✗ Current ratio improved✗ No share dilution✗ Gross margin improved✗ Asset turnover improved

Altman Z-score 87.7 (safe zone; above 3.0 = safe, below 1.8 = distress). Not meaningful for banks and insurers.

Analysts

Mean target
$650
+153%
Analysts
21
Strong Buy
Range
$188–$1,201
low – high
● price · ◆ mean target

Annual history

FYRevenueNet incomeFree cash flow
2025$0$-303.3M$-249.1M
2024$8.6M$-182.8M$-131.8M
2023$2.4M$-123.3M$-111.2M
2022$0$-214.0M$-185.5M

From the company's 10-K filings via SEC XBRL. 3-year revenue CAGR –.

Earnings

Next report: 2026-11-09 · before open · EPS est -3.63
24-1125-0225-0525-0825-1126-0226-0526-08-3.690.00
EstimateActual (beat)Actual (miss)
ReportEPS estActualSurprise
2026-08-06-3.69-2.87+22.2%
2026-05-07-3.68-3.20+13.0%
2026-02-19-3.13-3.50-12.0%
2025-11-05-3.49-3.36+3.7%
2025-08-04-3.36-3.31+1.4%
2025-05-02-3.21-3.29-2.5%
2025-02-28-2.82-2.94-4.3%
2024-11-06-1.95-2.75-40.9%

Stats refreshed 2026-10-21 18:16:06 ET from Yahoo Finance (yfinance). "–" means the data isn't available. Refresh now

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coteau

Independent research · Not investment advice · Important disclosures · Contact desk@coteau.app

Coteau Systematic Strategies publishes stock research and model portfolios. Results are hypothetical unless marked Live. Data: Yahoo Finance (15-min delayed), SEC EDGAR and the House Clerk.

Beta 0.9 · Oct 21, 2026