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SION

SION
$3.87
-6.75% Oct 21 close
Sector n/a Compare
-88%-51%-15%+22%+59%Oct 2025Oct 2026Apr 2026
SIONSPY
1W
-5.4%
1M
-35.5%
3M
-91.4%
6M
-91.0%
YTD
-90.6%
1Y
-90.9%

Live chart

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What they do

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial. Sionna Therapeutics, Inc. was incorporated in 2019 and is headquartered in Waltham, Massachusetts.

Healthcare · Biotechnology

For information only · Important disclosures

Grades vs sector

No sector grades for SION yet. Grades rank S&P 1500 stocks within their sector and refresh after each daily data run, so a stock outside that index or newly covered has none.

Our models

Not held by any of our 5 live models right now.

Quality Growth
Outside this model's universe or screens
Momentum Top 15
Outside this model's universe or screens
Momentum Blend
Not in the current book
New Highs Growth
Outside this model's universe or screens
Coteau Long Book
Not in the current book

News

More news
No recent headlines.

Key stats

52-week range$3.87 – $51.04
Valuation and fundamentals

Valuation & fundamentals

No US-GAAP 10-K/10-Q financials in SEC data (foreign filers report on Form 20-F, often under IFRS).

Earnings

Next report: 2026-11-05 · before open · EPS est -0.68
25-0325-0525-0825-1126-0326-0526-08-3.380.00
EstimateActual (beat)Actual (miss)
ReportEPS estActualSurprise
2026-08-06-0.65-0.66-2.0%
2026-05-12-0.50-0.60-19.1%
2026-03-02-0.53-0.46+14.0%
2025-11-05-0.47-0.46+3.2%
2025-08-11-0.45-0.41+9.6%
2025-05-12-0.45-0.62-37.8%
2025-03-20-2.68-3.38-26.1%
Insider trades
Ra Capital Management, L.P.
Director, 10% owner · 2026-09-17
Sell
$252.1K
Ra Capital Management, L.P.
Director, 10% owner · 2026-09-17
Sell
$21.6M
None
None · None
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Stats refreshed 2026-10-21 17:58:56 ET from Yahoo Finance (yfinance). "–" means the data isn't available. Refresh now

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coteau

Independent research · Not investment advice · Important disclosures · Contact desk@coteau.app

Coteau Systematic Strategies publishes stock research and model portfolios. Results are hypothetical unless marked Live. Data: Yahoo Finance (15-min delayed), SEC EDGAR and the House Clerk.

Beta 0.9 · Oct 21, 2026