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TWST

TWST
$142.70
+2.10% Oct 20 close
Sector n/a
-22%+115%+252%+389%+526%Oct 2025Oct 2026Apr 2026
TWSTSPY
1W
-5.7%
1M
-14.5%
3M
+48.9%
6M
+127.9%
YTD
+349.9%
1Y
+335.9%

Live chart

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What they do

Twist Bioscience Corporation manufactures and sells synthetic DNA-based products. It offers synthetic genes and gene fragments used in product development for therapeutics, diagnostics, chemicals/materials, food/agriculture, data storage. It provides NGS tools comprising library preparation kits, human exome kits, and fixed and custom panels.

Healthcare · Biotechnology

For information only · Important disclosures

Grades vs sector

No sector grades for TWST yet. Grades rank S&P 1500 stocks within their sector and refresh after each daily data run, so a stock outside that index or newly covered has none.

Our models

Not held by any of our 5 live models right now.

Quality Growth
Outside this model's universe or screens
Momentum Top 15
Outside this model's universe or screens
Momentum Blend
Not in the current book
New Highs Growth
ranked 2 of 589 · 12-month momentum 414.8%
Coteau Long Book
Not in the current book

News

More news
No recent headlines.

Key stats

52-week range$25.45 – $205.00
Valuation and fundamentals

Valuation & fundamentals

Bottom line
No cash-flow valuation
Model read-out from the numbers below, not advice. Score +0 (DCF counts double).
•Piotroski F-score4/9

Discounted cash flow

Trailing free cash flow is negative or missing, so a cash-flow DCF isn't meaningful by default. You can enter your own assumptions below.
Reverse DCFfor context, not a signal
Trailing free cash flow is zero or negative, so there's no growth rate to solve for. The price is betting on a turnaround to positive cash flow.
Edit assumptions · recalculates instantly
Your value per share–

Free cash flow = operating cash flow − capital spending, trailing 12 months (TTM to 2026-06-30). Growth default: average of 3-year revenue CAGR and latest revenue growth, capped at 30%. Years 6–10 fade linearly to terminal growth. Discount rate = 4.25% risk-free assumption + beta 1.00 (n/a) × 5% equity premium, kept within 7–13%. Bear: lower growth, +1 pt discount, 2% terminal. Bull: higher growth, −1 pt, 3%.

Multiples vs sector

Backlog (remaining performance obligations)

RPO
$21.9M
as of 2026-06-30
vs a year ago
+63%
YoY
× TTM revenue
0.05×
coverage
24-09
24-12
25-03
25-06
25-09
25-12
26-03
26-06

Contracted revenue not yet recognized, from SEC filings (XBRL tag RevenueRemainingPerformanceObligation).

Quality & financial health

Gross margin
52.0%
Operating margin
-33.6%
FCF margin
-21.6%
Net margin
-31.7%
Return on equity
-30.7%
Return on invested capital
-41.0%
Net debt / EBITDA
–
Current ratio
2.7×
Interest cover
-743.5×
Cash conversion (OCF/NI)
–
Piotroski F-score 4/9 · last two fiscal years
✗ Positive net income✗ Positive operating cash flow✓ Return on assets improved✓ Cash flow above net income✓ Long-term debt / assets fell✗ Current ratio improved✗ No share dilution✗ Gross margin improved✓ Asset turnover improved

Analysts

No analyst targets available.

Annual history

FYRevenueNet incomeFree cash flow
2025$376.6M$-77.7M$-75.6M
2024$313.0M$-208.7M$-69.2M
2023$245.1M$-204.6M$-170.3M
2022$203.6M$-217.9M$-226.2M
2021$132.3M$-152.1M$-139.3M
2020$90.1M$-139.9M$-152.1M

From the company's 10-K filings via SEC XBRL. 3-year revenue CAGR +22.8%.

Earnings

Next report: 2026-11-16 · before open · EPS est -0.20
24-1125-0225-0525-0825-1126-0226-0526-08-0.690.00
EstimateActual (beat)Actual (miss)
ReportEPS estActualSurprise
2026-08-03-0.28-0.56-98.5%
2026-05-04-0.53-0.60-12.6%
2026-02-02-0.52-0.50+3.9%
2025-11-14-0.50-0.45+10.0%
2025-08-04-0.57-0.47+18.1%
2025-05-05-0.56-0.66-17.4%
2025-02-03-0.63-0.53+16.5%
2024-11-18-0.69-0.59+14.9%
Insider trades
Laponis Adam
Chief Financial Officer · 2026-10-09
SELL
$384.8K
Leproust Emily M.
Director, Chief Executive Officer · 2026-10-05
SELL
$9.3K
Leproust Emily M.
Director, Chief Executive Officer · 2026-10-05
SELL
$30.2K
Leproust Emily M.
Director, Chief Executive Officer · 2026-10-05
SELL
$61.1K
Leproust Emily M.
Director, Chief Executive Officer · 2026-10-05
SELL
$59.4K
Leproust Emily M.
Director, Chief Executive Officer · 2026-10-05
SELL
$88.0K
Leproust Emily M.
Director, Chief Executive Officer · 2026-10-05
SELL
$205.8K
Leproust Emily M.
Director, Chief Executive Officer · 2026-10-05
SELL
$96.8K
Leproust Emily M.
Director, Chief Executive Officer · 2026-10-05
SELL
$368.8K
Werner Robert F.
Chief Accounting Officer · 2026-10-02
SELL
$279.9K
Cho Dennis
See Remarks · 2026-10-02
SELL
$1.8M
Leproust Emily M.
Director, Chief Executive Officer · 2026-10-02
SELL
$8.6M

Stats refreshed 2026-10-20 18:13:14 ET from Yahoo Finance (yfinance). "–" means the data isn't available. Refresh now

COTEAU

Independent research · Not investment advice · Important disclosures · Contact desk@coteau.app

Coteau Systematic Strategies publishes stock research and model portfolios. Results are hypothetical unless marked Live. Data: Yahoo Finance (15-min delayed), SEC EDGAR and the House Clerk.

Beta 0.9 · Oct 21, 2026